Students research modern DNA discoveries provided by the teacher as well as student selected discoveries. After summarizing each discovery, students reflect on the nature of science and identify and explain which NOS tenets are demonstrated in the DNA discoveries.

This is a hands-on activity to assess the students understanding of peptide and disulfide bonds formed during protein synthesis. Students demonstrate the process of dehydration synthesis by combining amino acids through peptide bonds creating molecules of water, and one protein amino acid strand. It can also be used to assess students understanding of the process of translation.

Express yourself through your genes! See if you can generate and collect three types of protein, then move on to explore the factors that affect protein synthesis in a cell.

Students will participate in a 5E lesson. To ENGAGE, students will connect their understanding of the characteristics of life to the fundamental molecule of life: DNA. To EXPLORE, students will extract DNA from fruit in a hands on (or video of a) lab, and then, students will act as Watson and Crick and use clues to discover the structure of DNA. In the EXPLAIN section, students will use slides to fill out guided notes on the structure of DNA and RNA. To ELABORATE on their understanding of DNA, students can participate in the CRISPR-Cas9 interactive and the Regulation of the Lactase Gene click and learn. Formative evaluations of students's ability to model DNA include (1) using an online interactive, (2) using their bodies as a class, and (3) using a cut and paste model. Finally, the summative EVALUATE is a DNA Model FlipGrid in which students use various materials to construct and explain the structure of DNA.

This lesson is designed for a high school biology class, as it is dependent on students having some prior knowledge of the structure of DNA. It reviews/teaches the key features of DNA structure by allowing students to use the engineering design process to create their own DNA models, compare/contrast provided models, and then edit/assess their own designs.

In this GRASP model performance task, students are asked to step into the role of a genetic researcher and apply their knowledge of transcription and translation to discover the cause, treatment, and possible cure for Sickle Cell Anemia. This task is designed for a high school biology course, but could be modified for other Life Science courses.