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Advances in Our Understanding of DNA & the Nature of Science
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CC BY
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Students research modern DNA discoveries provided by the teacher as well as student selected discoveries. After summarizing each discovery, students reflect on the nature of science and identify and explain which NOS tenets are demonstrated in the DNA discoveries.

Subject:
Health and Medical Sciences
Living Systems and Processes
STEM/STEAM
Science
Material Type:
Activity/Lab
Lesson Plan
Author:
Kathryn Williams
Date Added:
02/18/2021
Antiparallel structure of DNA strands
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CC BY-NC-SA
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DNA is composed of two strands of nucleotides held together by hydrogen bonding. The strands each run from 5' to 3' and run in antiparallel, or opposite, directions from one another.

Subject:
Living Systems and Processes
Science
Material Type:
Lesson
Provider:
Khan Academy
Provider Set:
Khan Academy
Author:
Sal Khan
Date Added:
07/16/2015
Bacteria Transformation
Read the Fine Print
Educational Use
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Students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria. They learn what role enzymes, DNA and genes play in the modification of organisms. For the particular model they work on, they isolate a mammal insulin gene and combine it with a bacteria's gene sequence (plasmid DNA) for production of the protein insulin.

Subject:
Science
Scientific and Engineering Practices
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Kimberly Anderson
Matthew Zelisko
Date Added:
09/18/2014
Biological Molecules
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CC BY-NC-SA
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In a 15 minute video, Paul Andersen describes the four major biological molecules found in living things. There are links to two worksheets and a transcript of the videoso you can create your own guided notes for students to complete while watching the video.

Subject:
Cross-Curricular
Living Systems and Processes
STEM/STEAM
Science
Material Type:
Homework/Assignment
Lecture Notes
Visual Media
Date Added:
11/30/2019
Biology: Chromosomes, Chromatids, Chromatin, etc.
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CC BY-NC-SA
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This 18-minute video lesson looks at the the vocabulary of DNA: chromosomes, chromatids, chromatin, transcription, translation, and replication. [Biology playlist: Lesson 8 of 71].

Subject:
Living Systems and Processes
Science
Material Type:
Lecture
Provider:
Khan Academy
Provider Set:
Khan Academy
Author:
Salman Khan
Date Added:
05/16/2019
Biotech Ethics Debate
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CC BY-NC-SA
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This lesson will be used to help students explore the bioethics of biotechnology. With a team, students choose a renewable alternative energy source such as cloning, stem cell research, DNA fingerprinting, or others and research the pros and cons of that biotechnology.

The team then splits into debate teams and draws straws to determine whether they are on the "pro" or "con" side. They will debate in front of the class allowing others in the class to learn about both sides.

Subject:
Living Systems and Processes
Science
Material Type:
Activity/Lab
Date Added:
11/23/2019
The Central Dogma: Replication, Transcription, and Translation 5E Lesson
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CC BY
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Students will participate in a 5E lesson. To ENGAGE, students will connect their understanding of similarities between parent and offspring to the fundamental molecule of life: DNA. To EXPLORE, students will participate in interactives to observe, analyze and summarize how genes are used to create proteins and traits. In the EXPLAIN section, students will take notes on DNA replication and the Central Dogma. To ELABORATE on their understanding of DNA, students will participate in a protein synthesis race (game) to practice transcription and translation. Formative evaluations of students's ability to explain the process of protein synthesis include (1) a protein synthesis and codon practice sheet, (2) a labeling activity, and (3) making a recording that models and explain the process. As an extension, students can apply their understanding of mRNA to explain how the Pfizer and Moderna COVID-19 vaccines work. Finally, int summative EVALUATE, students model replication, transcription, and translation as they build an organism!

Subject:
Health and Medical Sciences
Living Systems and Processes
Science
Scientific and Engineering Practices
Material Type:
Activity/Lab
Assessment
Homework/Assignment
Lecture Notes
Author:
Mary Hill
Date Added:
02/12/2021
Classifying Animals by Appearance Versus DNA Sequence
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CC BY-NC-SA
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The topic of this video module is how to classify animals based on how closely related they are. The main learning objective is that students will learn how to make phylogenetic trees based on both physical characteristics and on DNA sequence. Students will also learn why the objective and quantitative nature of DNA sequencing is preferable when it come to classifying animals based on how closely related they are. Knowledge prerequisites to this lesson include that students have some understanding of what DNA is and that they have a familiarity with the base-pairing rules and with writing a DNA sequence.

Subject:
Living Systems and Processes
Science
Material Type:
Lecture
Provider:
M.I.T.
Provider Set:
M.I.T. Blossoms
Author:
Megan E. Rokop
Date Added:
05/24/2019
DNA
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CC BY-NC-SA
DNA
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Learn about DNA (deoxyribonucleic acid). Overview of DNA bases, complementary base pairing, and the structure of the double helix.

Subject:
Living Systems and Processes
Science
Material Type:
Lesson
Provider:
Khan Academy
Provider Set:
Khan Academy
Author:
Sal Khan
Date Added:
09/22/2009
DNA Build
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Educational Use
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Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each other in a specific pattern, making a double helix. They investigate specific DNA sequences that code for certain physical characteristics such as eye and hair color. Student teams trade DNA "strands" and de-code the genetic sequences to determine the physical characteristics (phenotype) displayed by the strands (genotype) from other groups. Students extend their knowledge to learn about DNA fingerprinting and recognizing DNA alterations that may result in genetic disorders.

Subject:
Science
Scientific and Engineering Practices
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Janet Yowell
Malinda Schaefer Zarske
Megan Schroeder
Date Added:
09/18/2014
DNA | Cooking Up Science with Miss America
Unrestricted Use
CC BY
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Learn about DNA. Deoxyribonucleic acid is the blueprint for all living things, but it is so small we can’t usually see it. The role of DNA is to provide our cells information on building proteins; these proteins lead to our individual traits such as eye color, height, dimples, and so much more. The structure of DNA is a double helix and we can model this structure at home. This model is based on the work of Rosalind Franklin, a British Chemist who created an X-ray photograph that provided evidence of the double-helix structure of DNA molecules. We can also extract DNA from a living thing, such as a strawberry, at home. The components of this DNA are so small that it does not look like our model; however, with technology scientists can both see the structure and manipulate the structure to change proteins in organisms. The key concepts and terms explored in this episode include DNA, nucleotides, genes, and genetically modified organisms (GMO's).

Subject:
Living Systems and Processes
STEM/STEAM
Science
Material Type:
Activity/Lab
Lesson
Visual Media
Author:
Trish Reed
Date Added:
05/28/2021
DNA Forensics and Color Pigments
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Educational Use
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Students perform DNA forensics using food coloring to enhance their understanding of DNA fingerprinting, restriction enzymes, genotyping and DNA gel electrophoresis. They place small drops of different food coloring ("water-based paint") on strips of filter paper and then place one paper strip end in water. As water travels along the paper strips, students observe the pigments that compose the paint decompose into their color components. This is an example of the chromatography concept applied to DNA forensics, with the pigments in the paint that define the color being analogous to DNA fragments of different lengths.

Subject:
Science
Scientific and Engineering Practices
Material Type:
Activity/Lab
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
DNA Model
Unrestricted Use
CC BY
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Students are tasked with creating a model of DNA, which they then photograph and include a written explanation of how the model represents DNA.

Subject:
Living Systems and Processes
Material Type:
Lesson Plan
Author:
Rebecca Cannaday
Date Added:
07/19/2019
DNA: The Human Body Recipe
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Educational Use
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As a class, students work through an example showing how DNA provides the "recipe" for making our body proteins. They see how the pattern of nucleotide bases (adenine, thymine, guanine, cytosine) forms the double helix ladder shape of DNA, and serves as the code for the steps required to make genes. They also learn some ways that engineers and scientists are applying their understanding of DNA in our world.

Subject:
Science
Scientific and Engineering Practices
Material Type:
Activity/Lab
Lesson Plan
Teaching/Learning Strategy
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Denise W. Carlson
Frank Burkholder
Jessica Todd
Malinda Schaefer Zarske
Date Added:
09/18/2014