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DNA to Protein
Read the Fine Print
Educational Use
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Explore the relationship between the genetic code on the DNA strand and the resulting protein and rudimentary shape it forms. Through models of transcription and translation, you will discover this relationship and the resilience to mutations built into our genetic code. Start by exploring DNA's double helix with an interactive 3D model. Highlight base pairs, look at one or both strands, and turn hydrogen bonds on or off. Next, watch an animation of transcription, which creates RNA from DNA, and translation, which 'reads' the RNA codons to create a protein.

Subject:
Science
Material Type:
Data Set
Interactive
Lecture Notes
Provider:
Concord Consortium
Provider Set:
Concord Consortium Collection
Author:
The Concord Consortium
Date Added:
01/13/2012
Discovering Genes Associated with Diseases and Traits in Dogs
Conditional Remix & Share Permitted
CC BY-NC-SA
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In this video module, students learn how scientists use genetic information from dogs to find out which gene (out of all 20,000 dog genes) is associated with any specific trait or disease of interest. This method involves comparing hundreds of dogs with the trait to hundreds of dogs not displaying the trait, and examining which position on the dog DNA is correlated with the trait (i.e. has one DNA sequence in dogs with the trait but another DNA sequence in dogs not displaying the trait). Students will also learn something about the history of dog breeds and how this history helps us find genes.

Subject:
Living Systems and Processes
Science
Material Type:
Lecture
Provider:
M.I.T.
Provider Set:
M.I.T. Blossoms
Author:
Elinor Karlsson
Date Added:
05/24/2019
Don't Be a Square
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Educational Use
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After watching video clips from the Harry Potter and the Goblet of Fire movie, students explore the use of Punnett squares to predict genetic trait inheritance. The objective of this lesson is to articulate concepts related to genetics through direct immersive interaction based on the theme, The Science Behind Harry Potter. Students' interest is piqued by the use of popular culture in the classroom.

Subject:
Science
Scientific and Engineering Practices
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
Rachel Howser
Date Added:
09/18/2014
Engineering Nature: DNA Visualization and Manipulation
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Educational Use
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Students are introduced to genetic techniques such as DNA electrophoresis and imaging technologies used for molecular and DNA structure visualization. In the field of molecular biology and genetics, biomedical engineering plays an increasing role in the development of new medical treatments and discoveries. Engineering applications of nanotechnology such as lab-on-a-chip and deoxyribonucleic acid (DNA) microarrays are used to study the human genome and decode the complex interactions involved in genetic processes.

Subject:
Science
Scientific and Engineering Practices
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014
Engineering Out of Harry Situations: The Science Behind Harry Potter
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Educational Use
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Under the "The Science Behind Harry Potter" theme, a succession of diverse complex scientific topics are presented to students through direct immersive interaction. Student interest is piqued by the incorporation of popular culture into the classroom via a series of interactive, hands-on Harry Potter/movie-themed lessons and activities. They learn about the basics of acid/base chemistry (invisible ink), genetics and trait prediction (parseltongue trait in families), and force and projectile motion (motion of the thrown remembrall). In each lesson and activity, students are also made aware of the engineering connections to these fields of scientific study.

Subject:
Science
Scientific and Engineering Practices
Material Type:
Unit of Study
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Christine Hawthorne
Rachel Howser
Date Added:
09/18/2014
Fundamentals of Biology
Conditional Remix & Share Permitted
CC BY-NC-SA
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Fundamentals of Biology focuses on the basic principles of biochemistry, molecular biology, genetics, and recombinant DNA. These principles are necessary to understanding the basic mechanisms of life and anchor the biological knowledge that is required to understand many of the challenges in everyday life, from human health and disease to loss of biodiversity and environmental quality.

Subject:
Living Systems and Processes
Science
Material Type:
Full Course
Provider:
MIT
Provider Set:
High School Highlights
Author:
Eric Lander
Graham Walker
Hazel Sive
Michelle Mischke
Robert Weinberg
Sallie Chisholm
Tyler Jacks
Date Added:
10/22/2019
Gene Expression - The Basics
Unrestricted Use
CC BY
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Express yourself through your genes! See if you can generate and collect three types of protein, then move on to explore the factors that affect protein synthesis in a cell.

Subject:
Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
Ariel Paul
George Emanuel
John Blanco
Kathy Perkins
Mike Klymkowsky
Tom Perkins
Date Added:
08/20/2012
Gene Machine: The Lac Operon
Unrestricted Use
CC BY
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Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
George Spiegelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Date Added:
05/01/2010
Gene Machine: The Lac Operon (AR)
Unrestricted Use
CC BY
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Build a gene network! The lac operon is a set of genes which are responsible for the metabolism of lactose in some bacterial cells. Explore the effects of mutations within the lac operon by adding or removing genes from the DNA.

Subject:
Science
Material Type:
Simulation
Provider:
University of Colorado Boulder
Provider Set:
PhET Interactive Simulations
Author:
George Speigelman
Jared Taylor
John Blanco
Kathy Perkins
Noah Podolefsky
Date Added:
05/01/2010
The Genetic Basis of Inheritance and Variation
Conditional Remix & Share Permitted
CC BY-NC-SA
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The topic of this video module is genetic basis for variation among humans. The main learning objective is that students will learn the genetic mechanisms that cause variation among humans (parents and children, brothers and sisters) and how to calculate the probability that two individuals will have an identical genetic makeup. This module does not require many prerequisites, only a general knowledge of DNA as the genetic material, as well as a knowledge of meiosis.

Subject:
Living Systems and Processes
Science
Material Type:
Lecture
Provider:
M.I.T.
Provider Set:
M.I.T. Blossoms
Author:
Amjad Mahasneh
Date Added:
05/24/2019
Genetics
Unrestricted Use
CC BY
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This activity allows students to work through a series of games to learn about DNA, protein bases, and how they combine, dominant and recessive genes, Punnett Squares and genotypes, and phenotypes. 

Subject:
Living Systems and Processes
Material Type:
Assessment
Game
Interactive
Module
Author:
Jane Brown
Date Added:
07/12/2020
The Geniverse Lab Demo
Read the Fine Print
Educational Use
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The Geniverse software is being developed as part of a five-year research project funded by the National Science Foundation. Still in its early stages, a Beta version of the software is currently being piloted in six schools throughout New England. We invite you to try the current Beta version, keeping in mind that you may encounter errors or pages that are not fully functional. If you encounter any problem, it may help to refresh or reload the web page.

Subject:
Science
Material Type:
Activity/Lab
Data Set
Game
Interactive
Student Guide
Provider:
Concord Consortium
Provider Set:
Concord Consortium Collection
Author:
The Concord Consortium
Date Added:
12/11/2011
Human Biology - Genetics (Student's Edition)
Conditional Remix & Share Permitted
CC BY-NC-SA
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The Genetics Student Edition book is one of ten volumes making up the Human Biology curriculum, an interdisciplinary and inquiry-based approach to the study of life science.

Subject:
Living Systems and Processes
Science
Material Type:
Activity/Lab
Textbook
Provider:
CK-12 Foundation
Provider Set:
CK-12 FlexBook
Author:
Program in Human Biology, Stanford University
Date Added:
02/04/2011
Human Biology - Lives of Cells (Student's Edition)
Conditional Remix & Share Permitted
CC BY-NC-SA
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The Lives of Cells Student Edition book is one of ten volumes making up the Human Biology curriculum, an interdisciplinary and inquiry-based approach to the study of life science.

Subject:
Living Systems and Processes
Science
Material Type:
Activity/Lab
Textbook
Provider:
CK-12 Foundation
Provider Set:
CK-12 FlexBook
Author:
Program in Human Biology, Stanford University
Date Added:
02/04/2011
Imaging DNA Structure
Read the Fine Print
Educational Use
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Students are introduced to the latest imaging methods used to visualize molecular structures and the method of electrophoresis that is used to identify and compare genetic code (DNA). Students should already have basic knowledge of genetics, DNA (DNA structure, nucleotide bases), proteins and enzymes. The lesson begins with a discussion to motivate the need for imaging techniques and DNA analysis, which prepares students to participate in the associated two-part activity: 1) students each choose an imaging method to research (from a provided list of molecular imaging methods), 2) they research basic information about electrophoresis.

Subject:
Science
Scientific and Engineering Practices
Material Type:
Lesson Plan
Provider:
TeachEngineering
Provider Set:
TeachEngineering
Author:
Mircea Ionescu
Myla Van Duyn
Date Added:
09/18/2014